Herbs - Comfrey - Contraindications / Precautions / Warnings

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Contraindications / Precautions / Warnings

The internal consumption of comfrey may be prohibited by law.

Comfrey contains pyrrolizidine alkaloids that are hepatotoxic and can cause fatal veno-occulsive disease of the liver. Russian comfrey is carcinogenic to rats in low doses -- 0.5% to 8% of diet, but is also anticarcinogenic. S. officinale is less toxic than S. uplandicum although only two possible fatalities have ever been recorded in humans. These characteristics are usually absent from the dried herb. This plant has a long historical use.